Mononuclear phagocyte system

The Retikulohistiozytäre system ( RHS ), formerly also reticuloendothelial system (RES ), is the set of all cells of the reticular connective tissue, including those that are capable of phagocytosis and storage of materials or particles ( RHS ) cells. These are used as part of the immune defense and elimination of waste and foreign particles and pathogens. As antigen-presenting cells, these cells also perform certain functions in the specific defense.

The RHS consists of the reticular cells, fibrocytes, endothelial cells as well as histiocytes. These are immigrant in the reticular connective tissue and there wandering macrophages.

The RHS and the RES are systems in which the phagocytic cells of the organism are summarized belonging to the cellular immune defense. The term RES was proposed in 1924 by Ludwig Aschoff, RHS of Volterra and later by Thomas. The mononuclear phagocyte system (MPS ) is the youngest division, which was designed in the seventies of the 20th century by a group of pathologists. Each system sets certain priorities and includes certain cells or from. Granulocytes are included in either system.

The reticuloendothelial system (RES )

Aschoff divided the cells by increasing phagozytotischer activity:

Includes the RES in the strict sense 3 and 4, which includes RES in the broader sense 3 to 6

The mononuclear phagocyte system (MPS )

The MPS includes the cells of the developing series:

Furthermore expects Van Furth osteoclasts, microglia, as well as giant cells and epithelioid cells for MPS. Excluded are reticulum cells, dendritic cells and endothelial cells and fibroblasts.