MPP

  • 48134-75-4
  • 36913-39-0 ( iodide)

Yellow solid ( iodide)

Fixed ( iodide)

Soluble in water (> 10 mg / ml, iodide )

Iodide

Risk

27.5 mg · kg -1 ( LD50, mouse, unknown)

Template: Infobox chemical / molecular formula search available

1-methyl- 4- phenylpyridinium (MPP ) is a quaternary ammonium compound selected from the family of the bipyridine herbicides.

The neurotoxin MPTP is oxidized in the brain by the enzyme MAO -B to MPP . It causes Parkinson in primates by killing certain dopamine -producing neurons in the substantia nigra.

Use

The chloride salt of MPP was marketed as a herbicide under the trade name cyperquat and is structurally related to the herbicide paraquat.

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