Mucosectomy (Latin - Greek coinage, Latin mucosa - mucous membrane; Greek ek - prefix from out; tomein - cut; see ectomy ), also called " Endoscopic mucosal resection " (EMR), is the erosion of the mucous membrane of an organ. Thus, for example, in malignant tumors of the esophagus, the disease can be cured if the tumor is detected at a very early stage (so-called carcinoma in situ ( CIS) literally: " cancer in place " ), i.e., the tumor is not growing on the mucous out. However, the EMR is also seen quite critical in esophageal carcinoma.

A further development of this procedure is called Endoscopic Submucosal Dissection (ESD). It succeeds more often the mucosal tumor ' en bloc ' to remove what is important never to cut with regard to the principle recognized by a tumor. The ESD is mainly used for early gastric cancer with success. However, experience with this method is limited almost exclusively to Japanese Expert centers. Mucous membranes in the human body are very happy regeneration usually. The smaller the wound area, the faster ingrowth from the wound edges to cover the cells of the mucosa of the defect. This process leads - if no deeper tissue layers are violated - to no functional limitations after healing.

Early gastric carcinoma

In Japan, early gastric carcinoma has a much greater importance than in Germany, because it is much more common and there - including through screening strategies - the tumors are often discovered at an early stage.


Endoscopic mucosal resection for early cancers of the esophagus has been used for several years in Germany. In particular, the increasing incidence of adenocarcinomas are relevant here ( Pech et al., 2007 GOOD )

Vocal fold

Also on the vocal folds an addressed as mucosectomy method is used more frequently.