Myeloid-derived Suppressor Cell

Myeloid suppressor cells ( MDSCs - engl. Myeloid -derived suppressor cells) are a heterogeneous group of immature myeloid cells, which are capable of T cell- mediated immune responses to suppress. In normal cases ( health) to regulate the regeneration of the tissue and the immune response. In case of illness (such as inflammation or cancer), their numbers are increasing rapidly.

So far, some related to the influence of MDSCs are therapeutic approaches pursued to suppress, for example, the consequences of autoimmune diseases or transplant rejection Carcinombildung.

Itemization

• Cell type
• Immunology