Nancy Johnson was born in 1935 as Nancy Elizabeth Lee in Chicago. She attended the public schools of their home and then studied until 1953 at the University of Chicago. Then she continued her studies until 1957 at Radcliffe College in Cambridge (Massachusetts ) continued. Between 1957 and 1958 she graduated from the art history faculty of the University of London. She then worked as a teacher. Later she moved to New Britain in Connecticut, where she still lives today.
Politically, Johnson joined the Republican Party. Between 1977 and 1982 she was in the Senate from Connecticut. In 1980, she was delegate to the Republican National Convention in Detroit, was nominated on the Ronald Reagan as a presidential candidate.
1982 Johnson became the sixth electoral district of Connecticut in the U.S. House of Representatives in Washington DC selected. There it began on January 3, 1983 to succeed the Democrats Toby Moffett. After eleven elections she was able to complete in Congress until January 3, 2007, twelve coherent legislative periods. Since her real choice district was disbanded in 2002, she represented since January 3, 2003, extended the Fifth District. In the 2006 elections, they defeated the Democrat Chris Murphy. Between 1995 and 1997 she was chairman of the Committee on Standards of Official Conduct. During her time in Congress, Nancy Johnson, who described himself as an "independent voice" in Washington, mostly voted with their Republican faction. It supported, among others, the failed impeachment proceedings against President Bill Clinton and endorsed the Iraq war from the beginning. However, she was against the government energy policy under President George W. Bush.
After her time in the U.S. House of Representatives Johnson was a member of the faculty of political faculty of Harvard University. She is married to the physician Ted Johnson and lives in New Britain.