Osio Sopra is a municipality in the Province of Bergamo in the Italian region Lombardy with 5119 inhabitants ( 31 December 2012).
- The parish church of San Zeno dates from the Middle Ages. It is said that the church was built from the remains of a defunct sacred building.
- The Santuario della Madonna della Scopa dates from the 15th century and has been restored several times - most recently in the 20th century.
- The Palazzo Camozzi Andreini, also Palazzo delle Gigine, was built in the 18th century as a library.