In 1979 he moved to Tokyo and studied music history there. Since about 1987, he appeared with solo programs and in various band projects on the turntables and electric guitars. By 2007, he was involved in over 200 publications. His musical focus is on the new improvised music, where he attracted mainly by its radical electronic music sensation. The addition of the guitar to electronic equipment led him more and more to the art of reduction. Was it in the early groups, the sheer force of the sounds that impressed, as it is for now Otomo filtering and working out certain qualities of the sounds in the center. His delicate soundscapes evoke in recent times less to free jazz, as composers such as Morton Feldman. In addition, he also plays again and again in more traditional rock and jazz projects (eg with his New Jazz Ensemble ).
In 1999 he curated under the title " Mottomo Otomo " the Music Unlimited Festival in Wels.
During his numerous collaborations he worked together with Merzbow, Christian Marclay, John Zorn and Yamatsuka Eye. For the Donaueschingen Music Days 2005, he put together at the suggestion Reinhard Kager, the head of the now - Jazz series of the SWR2, a quartet with an electronics Sachiko M, trumpeter Axel Dörner and percussionist Martin Brandlmayr.
- Ground Zero (originally Ground -0), usually a nine-piece band project
- I.S.O trio with Ichiraku Yoshimitsu and Sachiko M
- Filament duo with Sachiko M
- Miira ni Narumade
- Otomo Yoshihide 's New Jazz Ensemble
- Otomo Yoshihide Quartet