Para-Dimethylaminobenzaldehyde

• Ehrlich's reagent
• P- dimethylaminobenzaldehyde
• 4 - (N, N-dimethylamino ) benzaldehyde
• DMABA

Bright yellow to green solid

Fixed

72-75 ° C

176 ° C at 22.7 hPa

• Poorly in water ( 2.18 g · l-1 at 25 ° C)
• Soluble in ethanol, diethyl ether, acetic acid and chloroform

500 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Dimethylaminobenzaldehyde, or more specifically, 4 - ( N, N- dimethylamino ) benzaldehyde is a benzaldehyde derivative, a N, N- dimethylamino carrying in the para position.

Use

A solution of 2 % dimethylaminobenzaldehyde in 20% hydrochloric acid is called the Ehrlich reagent or Ehrlich Pröscher reagent. It is used for the detection of primary amino groups, pyrrole and indole derivatives. The Ehrlich reagent was named after the discoverer, Paul Ehrlich.

In medicine, the Ehrlich 's reagent is used (Watson - Schwartz test and Hoesch test) in urine for the detection of porphobilinogen and urobilinogen.

In the pharmaceutical industry the Ehrlich reagent for the detection of pyrrole and indole derivatives (e.g., ergot alkaloids ) was used (van Urk reaction).

In Microbiology dimethylaminobenzaldehyde ( Kovacs reagent) is used for the detection of indole ( indole test). Since it is useful in this application for the detection of LSD, it has been in the drug scene achieved a certain notoriety.