Parinaud's syndrome

Under the Parinaud syndrome is the occurrence of vertical gaze palsy and other neurological deficits caused by damage to the cranial nerve nuclei in the region of the midbrain. It comes in addition to a lack of convergence reaction of the eyes, nystagmus and dilated pupil ( mydriasis) in the absence of a light reflex. The vertical gaze palsy the affected eye no consequence and command movements may go up, much less not carry down. However, this is possible reflex ( doll's head phenomenon). Cause is damage to the cranial nerves supplying or their nuclei in the region of the dorsal midbrain ( quadrigeminal plate, Prätektalregion ) by a brain tumor ( pinealoma ), multiple sclerosis, encephalitis or cerebral infarction after circulatory disorder. In infants and neonates the Parinaud syndrome is a characteristic sign of an increase in intracranial pressure. Since it usually comes to bilateral damage, both eyes are affected. The treatment is dependent on the triggering condition.

Others

The Parinaud's syndrome should not be using the Parinaud 's disease, an infection by the bacterium Francisella tularensis, confused. With the okuloglandulären syndrome Parinaud a unilateral conjunctivitis associated with lymph node swelling is called front of the ear and under the jaw. It occurs not only in the Parinaud disease but also in syphilis, tuberculosis, and fungal infections.

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