Polyamine

Under polyamines saturated open-chain or cyclic organic compounds are usually merged with terminal amino groups, interrupted by a varying number of secondary amino groups. Polyamines are colorless to yellowish depending on the chain length and are either liquid or solid.

The systematic designation according to IUPAC nomenclature is made with ... Aza.

Biogenic polyamines

Biogenic polyamines such as spermidine and spermine are small polycationic molecules. These may interact with ribonucleic acids and alter their properties. It is believed that polyamines may stabilize supercoiled DNA gefaltene and to a certain extent. The amount of polyamines in the cell appears to be stoichiometric with the amount of RNA. Further polyamines are mainly concentrated in the nucleus and in the ribosome. To a certain extent polyamines can replace K and Mg2 ions. Polyamines may play an essential role in nucleic acid, protein synthesis and cell development. Moreover, they can activate some enzymes such as the serine / threonine protein kinase CK2. The rate- limiting step in polyamine synthesis is accomplished through the ornithine decarboxylase and adenosylmethionine. In cancer, the rate of excretion of polyamines is significantly increased.

The polyamines 1,4- diaminobutane ( putrescine ) and 1,5- Diaminopentane ( cadaverine ) formed during decomposition processes by degradation of the amino acids ornithine and lysine, respectively. You wrote you earlier cadaveric poison - character and named it ptomaines. In fact, these biogenic amines are hardly toxic.

Use

Polyamines such as 1,2 -diaminocyclohexane, 4,4 '- diaminodiphenylsulfone, 1,5- diamino-2- methylpentane diamine, diethylene triamine, hexamethylene diamine, isophorone diamine, triethylene tetramine, and trimethylhexamethylenediamine, see, inter alia, as hardeners for epoxy resins and for the preparation of polyamides using. Di - and triamines having primary amino groups are converted by reaction with phosgene into the corresponding di-and tri - isocyanates used for the production of polyurethanes.

The polymeric polyamines inter alia, the polyethyleneimines and cationic flocculant containing quaternary ammonium groups include, calculated.