Proteinase K

  • CAS Number: 39450-01-6

39450-01-6

Risk

Proteinase K is a proteinase from the ascomycete Tritirachium album, which belongs to the family of subtilisin-like serine proteases. The enzyme attacks the peptide bonds at both the ends ( exopeptidase ), and in the interior ( endopeptidase ) of the proteins. Proteinase K is used for the degradation of proteins in cell lysates and in the release of nucleic acids.

Application Examples

  • Isolation of genomic DNA from bacteria
  • Isolating DNA from cells or tissue for the polymerase chain reaction ( PCR)
CAS registry number MEROPS Dangerous Substances Directive (67/548/EEC)
662689
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