Pterin

2-amino -3H- pteridin -4-one

Beige to yellow crystalline solid

Fixed

> 360 ° C

  • PKS1 2.20 ( 20 ° C)
  • PKS2 7.86 (20 ° C)

Attention

Template: Infobox chemical / molecular formula search available

Pterin is a derivative of pteridine and thus a heterocyclic compound. It occurs as a structural element in many biomolecules, such as in different color pigments of insects such as Leukopterin and xanthopterin, the cofactor biopterin or in the vitamin folic acid.

Properties

Pterin forms bright yellow crystals. When heated, it decomposes without melting. The compound exhibits two acid constants with PKS1 2.20 and pKa2 7.86 (in water at 20 ° C). The solubility in water is 0.175 g * l -1.

The compound can exist in two tautomeric structures.

Synthesis

The production of pterin is achieved by the reaction of 3- chloropyrazine - carboxylic acid methyl ester with Guanidiniumhydrogencarbonat.

Another synthesis is based on 2,4,5 -triamino -6- hydroxypyrimidine, which is reacted with glyoxal.

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