Pyriproxyfen

  • (RS )-4- Phenoxyphenyl2 -(2- pyridyloxy) propyl ether
  • (RS ) -2 - [1 - (4- phenoxyphenoxy ) propane -2 -yloxy ] pyridine

QP53AX23

Fixed

1.23 g · cm -3 ( 20 ° C)

45-47 ° C

0.29 MPa (at 20 ° C)

Attention

  • > 5 g · kg -1 ( LD50, rat, oral)
  • > 2 g · kg -1 ( LD50, rat, transdermal)

Template: Infobox chemical / molecular formula search available

Pyriproxyfen is a pesticide that is effective against arthropods. It is a derivative of pyridine and similar in structure to the related fenoxycarb.

In the United States it was introduced in 1996 against whiteflies on cotton plants, but also protects other crops. In Germany, Austria and Switzerland Pyriproxiyfen is not authorized as pesticides. It is effective against cat fleas and is used in combination with permethrin against the tropical rat mite.

Pyriproxyfen is an artificial juvenile hormone. It prevents the development of the larva to the adult animal, and thus reproduction.

Approvals

According to Directive 98/8/EC of 16 February 1998 biocidal products should be only allowed its agents in the annex (Annex I, IA and IB) of that Directive have been included ( for the defined product ). In accordance with the transitional arrangements (Article 16, paragraph 1 of Directive 98/8/EC ) the placing of biocidal products where these agents with stitch Date 14 Mai was, however, allowed to continue, not containing the active substances listed in the Annex to Directive 98/8/EC, 2000 already on the market were (also " existing active substances " called ).

Conforms to Regulation ( EC) 1896/2000 of 7 September 2000 Manufacturer had who wanted to applied for the inclusion of an "old drug " in Annexes I, IA and IB, reported that active substance by 28 March 2002 on the notification for the relevant product have. This deadline was extended by Regulation ( EC) 1687/2000 of 25 September 2002 to 31 January 2003. The " notified active substances " were allowed to remain on the market following up to the final decision on inclusion or non-inclusion in Annex I, IA and IB EU Directive 98/8/EC.

By Regulation ( EC) 2032/2003 of 4 November 2003, the active ingredient pyriproxyfen in the list (Annex II) of notified active substances has been following for product types 3 ( veterinary hygiene ) and 18 ( insecticides) was added. Commission Regulation ( EC) 1451/2007 of 4 December 2007über the second phase of the ten- year work program concerning the placing of biocidal products was the active ingredient pyriproxyfen in the final list (Annex II) of the part of the test program to be tested agents recorded, but only for the PT 18 (insecticides ).

With the adoption of Directive 2013/5/EU from February 14, 2013 is a decision before, include the substance of pyriproxyfen from 1 February 2015, the corresponding list (Annex I of Directive 98/8/EC ) for the PT 18 (insecticides ). The release of biocidal products containing the active ingredient, pyriproxyfen, is thus in the EU ( Switzerland has adopted this provision ) still allowed for the PT 18 (insecticides ) ( initially limited until January 31, 2025).

Trade names

Veterinary Medicine:

  • Monopreparations: Cyclio Spot on ad us. vet. (D, CH)
  • Combination preparations: Duowin ad us. vet. ( with permethrin )
Stereochemistry CAS registry number PubChem Anatomical Therapeutic Chemical Classification System Vapor pressure Dangerous Substances Directive (67/548/EEC)
665995
de