Pyrvinium

• {6-Dimethylamino-2-[2-(2,5-dimethyl-1-phenyl-1H-pyrrol-3-yl)ethenyl]-1-methylchinolin-1-ium}-[4,4'-methylenbis(3-hydroxynaphthalin-2-carboxylat)] (2:1)
• Bis{6-dimethylamino-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylchinolinium}-[4,4'-methylenbis(3-hydroxy-2-naphthoat)] (IUPAC)
• Pyrvinium emboat
• Viprynium emboat
• Pyrvinium hemiembonat

• 3546-41-6 ( Pyrviniumembonat )
• 548-84-5 ( Pyrviniumchlorid )

P02CX01

Light to dark orange solid ( Pyrviniumembonat )

Anthelmintic

Disturbance of sugar intake

• 210-215 ° C ( Embonate )
• 249-251 ° C ( Pyrviniumchlorid dihydrate, decomp. )

Practically insoluble in water and ether, soluble in ethanol, chloroform, and methoxyethanol

Pamoate salt hydrate

Attention

200 mg · kg -1 ( LD50, mouse, sc, Pyrviniumemboat )

Template: Infobox chemical / molecular formula search available

Pyrvinium is a drug against worm infections of the digestive tract in humans. Pyrvinium belongs to the group of quinolinium salts.

Medicine

The active ingredient is used as a salt of embonic ( pamoic ). Pyrviniumembonat or Pyrviniumemboat is a crystalline salt of bright orange -red color. In water, it does not dissolve. By suitable excipients Pyrviniumemboat is formulated as a coated tablet or suspension.

Application

Pyrvinium effective against pinworms ( Oxyuriasis ). The drug caused by disruption of the sugar intake of the worms dying off, as they are no longer able to adequately feed. Pyrvinium is apparently absorbed only a small percentage in the bloodstream.