Receptor activity-modifying protein

Receptor activity -modifying proteins ( Receptor activity -modifying proteins, short RAMPS ) are proteins that control by dimerization with a G protein-coupled receptor its conformation and thus its cellular transport. Currently, five different receptor activity -modifying proteins are known: RAMP1, RAMP2, RAMP3, and RAMP4 RAMP5.

Through its connection not only a transport of the receptor to the cell membrane can be achieved, but also the function of the receptor itself can be modulated. An example of this is the calcitonin receptor -like receptor ( calcitonin receptor- like receptor ), which as in the presence of RAMP1 as a receptor for the calcitonin gene-related peptide ( calcitonin gene-related Peptide receptor) and in the presence of RAMP2 receptor for adrenomedullin ( Adrenomedullinrezeptor ) functions.

  • Transport protein
  • Protein group
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