Reed–Sternberg cell
Sternberg - Reed giant cells ( after the Austrian pathologist Carl Sternberg and Dorothy Reed of American pediatrician Mendenhall ) created by the merger of Hodgkin cells.
These are blasts with light nucleoplasm, bean-shaped nucleus and large nucleolus. The binuclear forms often show a mirror- image arrangement of the nucleoli with surrounding wide cytoplasm; therefore they are also referred to as the " owl eyes ".
Sternberg - Reed giant cells are monoclonal B- lymphocytes from the germinal center of lymph nodes.
They are proving to lymphoma, Hodgkin's Lymphoma.
- Immunology
- Pathology
- Cell type