Ribose

  • D, D, D- aldopentose
  • L, L, L- aldopentose
  • D: 50-69-1
  • L: 24259-59-4
  • DL: 55058-43-0

Colorless and odorless solid

Fixed

0.8 g · cm -3

90-95 ° C.

Soluble in water

Template: Infobox chemical / molecular formula search available

Ribose (abbreviation: Rib ) is a sugar with five carbon atoms (ie, a pentose ). D -ribose is often found in nature, for example as part of the backbone of the RNA as well as in the biological energy carriers ATP ( adenosine triphosphate), ADP ( adenosine diphosphate ) and AMP (adenosine monophosphate ). In cells cAMP ( cyclic AMP ) is found as a second messenger for amplifying nervous or endocrine effects in the cell. The block adenosine ribose of these molecules is linked by the C1 atom with adenine. The phosphorylation takes place on 5'OH of not lying in the ring C5 atom.

The enantiomeric L- ribose has little meaning. Is usually meant by " ribose " D- ribose.

Ribose in the human organism may be synthesized from other monosaccharides through the pentose phosphate cycle.

Ribose may exist as five-membered ring ( furanose ) or a six-ring ( pyranose ) in aqueous solution to form a hemiacetal. At 31 ° C, the molecule is 58.5 % in the β -D - pyranoid to 21.5 % in the α -D - pyranoid to 13.5 % in the β -D - furanoid to 6.5 % against the α -D - furanoid and 0.05 % in the open-chain form. In aqueous solution, thus the β - pyranose form most frequently, since three of the four hydroxy groups are here in the equatorial plane.

211984
de