Riluzole

6 - ( trifluoromethoxy ) -1,3- benzothiazol- 2-amine (IUPAC)

N07XX02

White solid

> 25 g · l-1 in DMSO

Risk

67 mg · kg -1 ( LD50, mouse, oral)

Template: Infobox chemical / molecular formula search available

Riluzole ( Rilutek ® trade name ) is a drug that is used for the treatment of amyotrophic lateral sclerosis (ALS). It is extended in this disease the survival time of patients.

The chemical substance belongs to the group of benzothiazoles.

Pharmacological properties

Riluzole is a sodium channel blocker, and attenuates the effects of the neurotransmitter glutamate.