Simon Ignatius Pimenta studied Catholic theology, philosophy, pedagogy, and mathematics at the seminary of Bombay, at St. Pius College and the State University of Bombay. After his ordination in 1949 he was sent to Rome, where in 1954 a doctorate in the Department doctorate in canon law at the Pontifical Urban University.
From 1954 to 1959 he worked in the archdiocese of Bombay as a personal secretary to Archbishop Valerian Cardinal Gracias, Vice-Chancellor and temporary pastor. From 1959 he served as pastor the Cathedral Parish of the Cathedral of Bombay and at the same time taught liturgy at the Archbishop's Seminary, was rector of the Seminary of St. Pius X and provided the task of the Bishop Vicar for the training of priests offspring.
On June 5, 1971, he was named by Pope Paul VI. Titular Bishop of Bocconia and Auxiliary Bishop of Bombay. He received his episcopal consecration of the Archbishop of Bombay, Cardinal Gracias, on June 29th of the same year. Co-consecrators were Bishop Longinus Gabriel Pereira and the Bishop of Poona, William Zephyrine Gomes. On February 26, 1977 appointed Paul VI. Pimenta Titular per hac vice and Koadjutorerzbischof of Bombay. On September 11, 1978 he became Archbishop of Bombay. He provided this office until his resignation for reasons of age on 8 November 1996. He engaged in particular for pastoral and social affairs in his diocese with 12 hospitals, 44 health centers and numerous schools. From 1982 to 1988 he served as President of the Episcopal Conference of the Roman Catholic Church in India.
Pope John Paul II took him in 1988 as a cardinal priest with the titular church of Santa Maria Regina Mundi a Torre Spaccata in the College of Cardinals to. Cardinal Pimenta took in 1990 at a Synod of Bishops at the Vatican in part. 1990 Pimenta was one of three presidents of the Synod of Bishops on the formation of priests in Rome. Simon Cardinal Pimenta took because of the age limit neither the conclave in 2005 in part at the conclave of 2013. He last lived in a home for retired clergy, where he died on July 19, 2013 at the age of 93 years.