Sodium bis(trimethylsilyl)amide

• Sodium hexamethyldisilazide
• NaHMDS

White to light yellow solid

Fixed

171-175 ° C

Soluble in hexane, toluene, and ether

Risk

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Sodium bis (trimethylsilyl) amide is a chemical compound from the group of Trimethylsilylamide and the sodium salt of hexamethyldisilazane.

Production and representation

Sodium bis (trimethylsilyl) amide can be obtained by reaction of hexamethyldisilazane with a solution of sodium amide in benzene.

Properties

Sodium bis (trimethylsilyl) amide is a white, to hydrolysis, a crystalline solid that is soluble in many organic solvents. It reacts with water to form sodium hydroxide and hexamethyldisilazane.

Use

Sodium bis (trimethylsilyl) amide is used for the production of carbenes of the amination of the production of sulfenamides and lanthanide complexes. It also serves as a strong base for deprotonation or base -catalyzed reactions, for Enolatbildungen, base for Wittig reactions and together with alkyllithium as a super base component.