Sulfadoxine

Sulformetoxinum

Crystalline solid

Sulfonamides

Fixed

190-194 ° C

Slightly soluble in water, low solubility in methanol and ethanol, insoluble in diluted mineral acids and alkali bases

Attention

5200 mg · kg -1 ( LD50, mouse, oral)

Template: Infobox chemical / molecular formula search available

Sulfadoxine is an antibiotic from the group of sulfonamides.

Synthesis

For the synthesis of 4- Acetamidobenzolsulfonsäurechlorid is reacted with 4-amino- 5 ,6- dimethoxypyrimidine and then removed the acetyl alkaline.