The synaptic vesicle protein 2A (English synaptic vesicle glycoprotein 2A, cast off SV2A ) is a ubiquitous in the brain vesicle protein SV2 protein family, which is encoded in the human genome on the gene SV2A. The protein is site of action of the anticonvulsant drug levetiracetam.


SV2A is involved in neuronal impulse conduction. The exact molecular mechanism of action is not known, but it is assumed that the vesicle protein 2A makes vesicle fusion capable, allowing them to fuse with the presynaptic membrane and release their neurotransmitters into the synaptic cleft.