Tiapride

N-2- (diethylaminoethyl )-5- methylsulfonyl -2- methoxybenzamide

  • 51012-32-9
  • 51012-33-0 (hydrochloride)

N05AL03

Antidopaminergikum for the treatment of dyskinesias

4840 mg · kg -1 ( LD50, rat, oral)

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Tiapride ( N-2- (diethylaminoethyl )-5- methylsulfonyl -2- methoxybenzamide ) is a Antihyperkinetikum with a plasma half-life of 2.9 to 3.6 hours. It is one of the typical neuroleptics.

It is used in compulsive movement disorders:

  • For the treatment of tic disorder in Tourette's syndrome,
  • In dyskinesias eg chorea,
  • And - although of a neuroleptic - at the damage caused by other antipsychotics, movement disorders, such as akathisia and dyskinesia ( eg, haloperidol -induced "shuffling ").

But apparently it has insufficient or no typical neuroleptic effects ( ie antipsychotic effects).

Trade names

Tiaprid is available under the name Delpral commercially available in Germany, Austria and Switzerland as well as a generic in Austria.

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System
226549
de