Tolnaftate

O- naphthalene-2 ​​-yl [ methyl- (3 - methylphenyl) amino] methanthioat (IUPAC)

D01AE18

Antifungal

111 ° C.

Template: Infobox chemical / molecular formula search available

Tolnaftate is a drug that is used as a topical antifungal agent. This is a thiocarbamate.

Areas of application

Tolnaftate has a fungicidal effect on dermatophytes, yeasts against but it is ineffective.

Effect

It inhibits sterol synthesis by blocking the enzyme squalene epoxidase.

Swell

• C.-J. Estler ( Founder) and H. Schmidt ( eds.): pharmacology and toxicology. 6th edition, Schattauer, 2007, p 843