Toxic oil syndrome

The Spanish oil syndrome ( engl. Toxic Oil Syndrome ( TOS), Spanish síndrome del aceite tóxico ), created in 1981 as a result of mass poisoning by contaminated cooking oil. This diseased approximately 20,000 people, more than 200 died a short time later.

Prehistory

Denatured with aniline rapeseed oil was marketed as edible oil in the trade and sold in Spain from street vendors.

Symptoms

Among other things, the following symptoms occurred:

• Myalgia (general muscle pain )
• Peripheral eosinophilia ( mitochondria wealth in the blood )
• Pulmonary ( accumulation of fluid and cellular components in the lung)
• Scleroderma ( Bindegewebsverhärtung the skin alone or skin and internal organs )

Toxicology

The exact mechanism of poisoning and thus the toxic agent is still unclear. After the aniline hypothesis has not been confirmed, including a connection with fatty acid esters of 3 will now - (N- phenylamino ) -1,2- propanediol (PAP ) and autoimmune mechanisms discussed.