Transferase

Transferases ( from Latin transferre, carry over ' ) are enzymes of the second class of enzymes according to the systematic nomenclature of enzyme Commission of the International Union of Biochemistry (IUB ) and catalyze the transfer of a functional group X (eg a methyl group or phosphate group ) from a donor A to an acceptor B:

The donor is often a coenzyme.

Nomenclature

Systematically correct names of transferases are formed according to the following pattern: " donor: acceptor Gruppetransferase ". However, other names are common. The usual names of transferases are formed as follows: " acceptor Gruppetransferase " or " donor Gruppetransferase ". For example, a DNA methyltransferase is a transferase that catalyzes the transfer of a methyl group to a DNA acceptor.

EC- classification

Transferases in the EC numbers classification system under EC 2 -. -. - Categorized. Transferases can be grouped under nine specific subclasses:

  • EC 2.1. -. - Includes enzymes that transfer one- carbon groups
  • EC 2.2. -. - Comprises enzymes that transfer aldehyde or ketone groups
  • EC 2.3. -. - Includes acyltransferases
  • EC 2.4. -. - Includes glycosyltransferases
  • EC 2.5. -. - Comprises enzymes, which transfer alkyl or aryl groups,
  • EC 2.6. -. - Includes enzymes that transfer the nitro groups
  • EC 2.7. -. - Includes enzymes that transfer phosphorus-containing groups ( kinases)
  • EC 2.8. -. - Includes enzymes that transfer sulfur-containing groups
  • EC 2.9. -. - Includes enzymes that transfer the selenium-containing groups

Examples

  • Transglutaminase ( EC 2.3.2.13 )
  • Hexokinase ( EC 2.7.1.1 )
  • Glycogen phosphorylase ( EC 2.7.1.37 )
  • Pyruvate kinase ( EC 2.7.1.40 )

Other enzyme classes

  • Oxidoreductases ( EC 1 -. -. - )
  • Hydrolases ( EC 3 -. -. - )
  • Lyases ( EC 4 -. -. - )
  • Isomerases ( EC 5 -. -. - )
  • Ligases ( EC 6 -. -. - )
DNA-Methyltransferase Carbon (disambiguation)
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