Uri Alon

Uri Alon (born 1969 ) is an Israeli physicist and professor of systems biology at the Weizmann Institute.

Alon graduated from the Hebrew University, where he received his doctorate in physics at David Mukamel in Theoretical. As a post - graduate student he was at Princeton University. After that, he was at the Weizmann Institute, where he became Associate Professor in 2004 and Professor in 2008.

He dealt with gene regulatory networks in E. coli and resulted in their 2002 analysis the term motif network ( Network motif). They act for example as generators temporal patterns ( oscillators ), filter, pulse generators, response amplifier and examples are feed-forward loops (FFL ), single input modules ( SIM), Negative autoregulation (NAR, and positive PAR). They are also found in other biological networks (such as in the nervous system ). He studied in his laboratory and the evolution of biological networks ( experimentally and theoretically ).

In his laboratory he built up a library of over 2000 E. coli strains in which fluorescent proteins are used as indicators of the promoters in the gene expression of E. coli. They are also working on methods hundreds of proteins in living human cells and their dynamics simultaneously observed.

In 2007 he became a member of the European Molecular Biology Organization ( EMBO). In 2004 he was awarded the Overton Prize from the International Society for Computational Biology, 2001, EMBO Young Investigator Award, the 2003 Morris L. Levinson Award in Biology and 2000 he was a Moore Fellow at Caltech.

Writings

  • An introduction to systems biology: design principles of biological circuits, Boca Raton: Chapman & Hall / CRC 2007
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