UDP - glucuronate decarboxylase ( UGD ) is the enzyme that catalyzes the removal of carbon dioxide from UDP - glucuronate in eukaryotes. The resulting UDP -xylose is necessary for the biosynthesis in plants of the xylose and other pentoses. Vertebrates require UDP -xylose alone for the production of glycosaminoglycans (cartilage ). UGD is localized in the membrane of the Golgi apparatus.

Catalyzed reaction

⇒ CO2

UDP - α -D - glucuronate is converted to UDP - α -D-xylose.