Very Low Density Lipoprotein

Very low density lipoprotein (VLDL ) is a component of blood plasma, and is used for transport of triglycerides, cholesterol and phospholipids from the liver to the tissues. On its way it transforms itself by the gradual release of triglycerides from VLDL to LDL.

VLDLs are very low density lipoproteins, the synthesis takes place in the liver. Your lipid proportion is 85-90 %, and its protein content accordingly at 10-15 %. The apolipoproteins ApoB 100, ApoE and stabilize the VLDL. After entering into the bloodstream it comes to interactions with HDL, which deliver the apolipoproteins ApoE and ApoC -II to the VLDLs. The latter mediates the cleavage of free fatty acids of triacylglycerols by lipoprotein lipase, which is active in the capillary endothelium. After the delivery of triacylglycerides arises from the releasing VLDL lipoproteins, intermediate density lipoprotein ( IDL), whose density is higher because of the lower fat content.

VLDLR is the abbreviation for the " very low density lipoproteinreceptor " a receptor which binds to VLDL.