Victor Ambros

Victor Ambros ( born 1953 in Hanover, New Hampshire) is an American biologist and Professor of Molecular Medicine at the University of Massachusetts Medical School.

Life

Ambros grew up in Hartland, Vermont. He earned a bachelor's degree in biology in 1975 from the Massachusetts Institute of Technology (MIT ) in Cambridge, Massachusetts, in 1979 just there with David Baltimore a Ph.D. in Biology with a thesis on the genetics of poliovirus. As a postdoctoral fellow, he also remained at MIT and worked with Gary Ruvkun in the laboratory of H. Robert Horvitz. A first professorship was Ambros 1985 at Harvard University in Cambridge, Massachusetts, before he was offered a professorship at Dartmouth College in 1992. In 2008 he moved to the University of Massachusetts Medical School in Worcester, Massachusetts.

Work

Ambros and his research group reported 1993 on the first microRNA ( a gene product of lin -4), which plays an important role in the development of the nematode Caenorhabditis elegans. Later it became clear that non-coding RNA in this class also occur in higher organisms and play an important role in gene regulation. Recent work Ambros ' deal with the micro - RNA -mediated regulation in the development of animals ( including fruit flies ) and in various human diseases.

Awards (selection)

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