Vroman effect

The Vroman effect, Vroman named after Leo, is a phenomenon which occurs during the adsorption of proteins from the blood serum to a surface. The proteins with the highest mobility reach the first surface; however, they are replaced by the following proteins, which although having a lower mobility, but a higher affinity for the surface. A typical example is fibrin, which is adsorbed on biopolymers, and is subsequently replaced by other proteins. This leads to a decrease of the fibrinogen level in blood serum.

Swell

  • L. Vroman: Effect of Adsorbed protein on the Wettability of Hydrophilic and Hydrophobic Solids. (PDF) In: Nature. 196, No. 196, November 3, 1962, pp. 476-477. doi: 10.1038/196476a0.
  • Blood
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