She had her film debut in 1955 in a Telugu film directed by D. Yoganand. The audience was thrilled by her dance performance and later made her the star of the Hindi film of the 1950s and 1960s. In Guru Dutt's autobiographical film Pyaasa (1957 ) she plays a prostitute. Also in some other Guru Dutt films, such as Kaagaz Ke Phool (1959 ), she played the lead role. Often, they also appeared as a positive counterweight to dramatic roles of other actors, so with Meena Kumari in Sahib Bibi Aur Ghulam (1962). She played under the direction of Satyajit Ray in Abhijan (1962, with Soumitra Chatterjee ). The highlight of her career, she reached in Guide (1965, with Dev Anand ) by Vijay Anand in the role of a woman who leaves her husband impotent, to live with her lover, who will assist you in the career as a dancer. Her portrayal is considered outstanding and it managed to win the sympathy of the audience for the film character despite antitraditionalistischem plot. Subsequent ambitious roles were less successful, but she had commercial success with Teesri Kasam, for example (1966, with Raj Kapoor ). Waheeda Rehman continued to play character roles, on several occasions it was in the 1970s and 1980s " film nut " by Amitabh Bachchan. Yash Chopra cast her in his film Lamhe (1991 ) and placed it prominently with a reminiscence of her dance performance in Guide out. After that, Waheeda Rehman first moved back from the film business, but it seems since 2005 to become active again in Bollywood.
Rehman is two times winner of the Filmfare Awards for Best Actress and won the 1993 Filmfare Award for lifetime achievement.