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Xanthosinmonophosphat (XMP) is a nucleotide and the phosphate esters of the nucleoside xanthosine. It is a metabolic product, which occurs in the two-step biosynthesis of guanosine monophosphate (GMP).
Xanthosinmonophosphat is formed in the NAD -dependent dehydration of inosine monophosphate (IMP) by inosine monophosphate dehydrogenase ( IMPDH ). Through the transfer of glutamine Amidstickstoffes XMP is subsequently converted to GMP by GMP synthase. This reaction is driven by the hydrolysis of adenosine triphosphate to adenosine monophosphate and pyrophosphate. Despite the chemical belonging to the ribonucleotides Xanthosinmonophosphat itself is not part of the ribonucleic acid.
XMP acts as guanosine monophosphate as a flavor enhancer for the sensation of taste " salty".
Enzymes include the XMP as a substrate or reaction product include:
- IMPDH ( EC 184.108.40.206 )
- Xanthine phosphoribosyltransferase ( EC 220.127.116.11 )
- GMP synthase ( EC 18.104.22.168 )
- GMP synthase ( glutaminhydrolysierend ) ( EC 22.214.171.124 )