XDR stands for:
- The ISO 4217 currency code of the Art Special Drawing Right
- External Data Representation, a communication standard by Sun Microsystems
- XML Data Reduced, a former schema language (XML)
- XDomainRequest, an AJAX technology for cross-domain access in the field of web development. For AJAX see Ajax ( programming).
- XDR DRAMs, a particular type of computer memory
- Extensive drug resistant germs, which almost completely outside the ambit of modern antibiotics