25I-NBOMe

  • 2 - (4 -iodo-2 ,5- dimethoxyphenyl) -N-[ (2-methoxyphenyl ) methyl] ethanamine
  • 2C-I - NBOMe
  • ( [ 11C] Cimbi -5)
  • 919797-19-6 (base)
  • 1043868-97-8 (hydrochloride)

White solid (hydrochloride)

157.3 ° C ( hydrochloride)

Template: Infobox chemical / molecular formula search available

25I - NBOMe ( NBOMe - 2C-I or ) is a research chemical with hallucinogenic effects, which counts because of their structure to the material groups of Phenol and phenethylamines. The effect is returned in part to the properties of the 25I - NBOMes a potent agonist at the serotonin 5-HT2A Rezeptores. 25I - NBOMe is a derivative of 2C-I.

History

25I - NBOMe was developed in 2003 by Ralf home at the Free University of Berlin as part of his doctoral thesis "Synthesis and pharmacology of potent 5 -HT2A receptor agonists with N-2- methoxybenzyl partial structure ". The 11C -labeled compound ( [ 11C] Cimbi -5) of 25I - NBOMe was synthesized at the University of Copenhagen and validated as radiotracers for positron emission tomography (PET).

Pharmacodynamics

25I - NBOMe binds with the following Ki values ​​to the individual receptors:

Legal status

  • Germany
CAS registry number PubChem Erowid Digital Object Identifier PubMed Central
13155
de