Cisatracurium besilate

  • 2,2 '- [ pentane -1 ,5- diylbis ( oxycarbonylethylen ) ] bis [ (1R, 2R) - 1 - (3,4- dimethoxybenzyl) - 6,7- dimethoxy- 2-methyl- 1, 2, 3,4- tetrahydroisoquinolinium ] - dibenzensulfonat (IUPAC)
  • Cisatracurii besilas (Latin )
  • C53H72N2O122 cisatracurium
  • C65H82N2O18S2 Cisatracurium Besylate
  • 96946-41-7 cisatracurium
  • 96946-42-8 Cisatracurium Besylate

M03AC11

Muscle relaxants

  • 929.15 g · mol -1 cisatracurium
  • 1243.51 g · mol -1 Cisatracurium Besylate

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Cisatracurium corresponds to the cis -cis isomer of the racemate atracurium. It does not lead to histamine release, in contrast to atracurium. The reduction will be 80-90% by Hofmann elimination and only to a small extent by nonspecific esterases in the plasma. The achieved levels of laudanosine are lower than for atracurium. As drug cisatracurium is used primarily as benzenesulfonic acid salt ( besylate ) is used. The name was from Burroughs Wellcome (now GlaxoSmithKline) designed. The preparations Nimbex name stands for " excellent neuromuscular blockers " (see muscle relaxant ) ( engl. excellent Neuromuscular blocker ).

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System DrugBank Atracurium besilate Blood plasma Active ingredient PubMed Central
190752
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