Cloxacillin

(2S,5R,6R)-6-{[3-(2-Chlorphenyl)-5-methyl-oxazol-4-carbonyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsäure (IUPAC)

  • 61-72-3
  • 7081-44-9 (sodium salt monohydrate )

J01CF02, QJ51CF02, QS01AA90

Isoxazolylpenicillin

Risk

Template: Infobox chemical / molecular formula search available

Cloxacillin is an antibiotic effective drug. Substance from the group of β -lactam antibiotics is one of the penicillinase -resistant penicillins. Cloxacillin is today mainly used in veterinary medicine in Germany is not a preparation for the people in the trade.

As an application areas especially infections with penicillin - resistant staphylococci are given, such as skin and soft tissue infections (impetigo, cellulitis, pyomyositis ), endocarditis, septicemia, pneumonia, osteomyelitis, etc. The action spectrum corresponds to the other Isoxazolylpenicilline, including oxacillin, dicloxacillin, flucloxacillin and methicillin. include Cloxacillin is different from oxacillin by an additional chlorine atom on the phenyl ring.

Cloxacillin the list of essential drugs of the World Health Organization is listed. It can be administered intravenously or orally.

Trade names

  • Cloxapen, Tegopen Orbenin (USA)
  • Veterinary medicine: Aniclox, Cloxaben, Cloxamycin, Cloxin, Gelstamp, Klato clox, Mammin TS forte, Mastipent (combi ), neoclox md (Combi ), Orbenin, Penivet, Vetoscon, Vetriclox, Wedeclox
CAS registry number PubChem Anatomical Therapeutic Chemical Classification System DrugBank Dangerous Substances Directive (67/548/EEC) Active ingredient Meticillin Phenyl group WHO Model List of Essential Medicines
194442
de