Dexibuprofen
- ( ) - ( 2S ) -2 - [ 4 - (2 -methylpropyl ) phenyl] propanoic acid
- ( ) - ( 2S ) -2 - [ 4 - (2 -methylpropyl ) phenyl ] propionic acid
M01AE14
White crystals
Non-steroidal antiinflammatory
Fixed
49-53 ° C
- Insoluble in water
Template: Infobox chemical / molecular formula search available
Dexibuprofen is the (S) -enantiomer of the racemate ibuprofen, which was first patented in 1996. Dexibuprofen ibuprofen as a cyclooxygenase inhibitor as the drug ( non-steroidal anti-inflammatory agent ) is used.
As it should be about twice as effective, one comes out with a smaller amount of drug per tablet. In addition, the effect is somewhat faster than the racemate ibuprofen.
Since the endogenous 2- arylpropionyl -CoA epimerase, the racemized dexibuprofen can to ibuprofen, the therapeutic benefits of dexibuprofen against ibuprofen are controversial. Dexibuprofen to cause fewer side effects, but is also questioned by other studies.