Kim Nasmyth

Kim Nasmyth Ashley ( born October 18, 1952 in London, England ) is a British biologist and molecular geneticist cell. He is a professor of biochemistry at the University of Oxford in Oxford, United Kingdom.

Life

Nasmyth attended Eton College and studied at the University of York in York, England, biology. He obtained in 1977 with the thesis " DNA replication in the fission yeast Schizosaccharomyces pombe " at the University of Edinburgh in Edinburgh, Scotland a Ph.D.. Postdoctoral he worked with Benjamin D. Hall at the University of Washington in Seattle, Washington, and then. a scholarship from the Robertson Foundation at Cold Spring Harbor Laboratory in Cold Spring Harbor, New York From 1982 to 1987 he was a research assistant at the Laboratory of Molecular Biology in Cambridge, United Kingdom. In 1988 he moved to the Research Institute of Molecular Pathology (IMP, Research Institute of Molecular Pathology ) in Vienna, Austria, which he headed from 1997. At the University of Vienna, he additionally held an honorary professorship for Molecular Genetics. 2005 Nasmyth was appointed professor of biochemistry at the University of Oxford in Oxford, United Kingdom.

Work

Nasmyth has special contributions to the study of the regulation of mitosis. He characterized the anaphase - promoting complex, mitotic cyclins are degraded by the cohesin complex that connects the sister chromatids prior to mitosis each other, and a new proteolytic mechanism, the connection of sister chromatid breaks up quickly at the onset of mitosis. Nasmyth's work has considerable importance for the understanding of chromosomal non- disjunction in cancer cells and in genetic disorders. Nasmyth's most important model organisms are yeasts.

Awards (selection)

• Membership in the Academia Europaea