Louis Henri Vaquez
Louis Henri Vaquez ( born August 27, 1860 in Paris, France, † 1936 in Paris) was a French internist and cardiologist.
Family
His father ran according to family tradition, a merchant business for silk fabrics, together with his two brothers, who later led the family business continues.
Education and work
Vaquez attended the Lycée Condorcet in Paris and then decided to study medicine. Fernand Widal (1862-1929) was his classmate and later became known by the discovery of typhoid fever pathogen detection. After graduating Vaquez worked since 1884 as the Internal hôpitaux in the Paris hospitals, received the 1889 Silver Medal of Internal Medicine, 1895 was admitted as a Doctor of hôpitaux and 1898 as associate professor and member of the medical faculty. It was not until 1918/1919 he was appointed professor and member of the Académie de Médecine. Vaquez worked mainly in the Paris hospitals St. Antoine and La Pitié, his main interest was cardiovascular disease, also a result of his collaboration with Pierre Potain.
Performance
1892 Vaquez had polycythemia described as an independent clinical syndrome, it was written by William Osler ten years later rediscovered ( Vaquez - Osler syndrome). After the death of Potain a friendship with Joseph Babinski, 1901 for the joint description of a particular form of clinical course of syphilis with nerve and vascular lesions led ( Babinski Vaquez syndrome) developed. From 1907 to Vaquez dealt with the clinical sphygmomanometry and hypertension and designed methodically different measuring equipment ( palpation 1908 auscultatorily 1921 oscillometrically 1931). In addition, he tried to develop the theory and practice of "medium" arterial pressure.
His interest in graphic recording methods led to investigations of arrhythmia and the introduction of electrocardiography in France. With Bordet, he also worked on the cardiac radiology. Vaquez checked the nitrate therapy in the high-pressure disease, led in France, the ouabain - injection, for the treatment of heart failure and examined blood diseases ( leukemia and polyglobulias ).
Since 1908 Vaquez editor of the leading cardiology journal Archives of France des maladies du cœur of Vaisseaux et du sang was.
Vaquez - Osler Syndrome
" There are among the various chronic cyanosis, which have not been differentiated, a completely separate class, which is characterized by a prädominantes symptom, excessive polycythemia - and you can assign these polycythemia a whole range of disorders hardly be explained otherwise could. (...) In these patients, we usually notice a unique and sometimes striking increase in volume of the liver and spleen. "
Vaquez observed in 1892 for the first time a case of severe red blood cell proliferation, cyanosis and enlargement of the spleen and liver and ordered the symptoms of a new class of hematological diseases, the disease of symptomatic polyglobulias limited (eg, congenital heart defects with cyanosis, height adjustment). William Osler believed regardless of 1903 to make an original observation, but rediscovered the disease already described by Vaquez and named it polycythemia vera. The etiology suspected Vaquez in this primary idiopathic polycythemia overactivity of the hematopoietic system, neoplastic or genetic factors can not be excluded.
The symptoms also includes an increase in the total amount of blood, a crimson, plethoric complexion, fundus changes, cardiac hypertrophy, general bleeding or thrombosis, structural changes of the long bones and skull, and neuropsychiatric disorders.
Babinski Vaquez syndrome
Obsolete term for a particular form of clinical course of syphilis ( tabes Spätsyphilis. fruste ) with nerve and vascular lesions. Narrow, unrounded and immobile pupils, an aortitis with multiple aneurysms, attenuated or absent Achilles and patellar reflexes and a chronic meningo - encephalitis with lymphocytic pleocytosis in the cerebrospinal fluid are characteristic.
Works
- Sur une forme de Spéciale d' cyanosis s'accompagnant hyperglobulia excessive et persistante. Soc Biol Paris (C. R. ) 44 (1892 ) 384
- Sphygmomanometry clinique. Bull Med 17 (1903) 279
- Sphygmic signal. Soc Biol Paris (C. R. ) 64 (1908 ) 875
- Les arythmies ( with Bordet ). 1911
- Maladies de cœur. Paris 1921
- Une nouvel indicateur de pression: " Le Kymométre " (. , Et al ). Press Med 39 (1931) 1802
- De la mesure de la moyenne par la méthode pression oscillométrique. Press Med 39 (1931) 1309
- Un syndrome hypertensif nouveau, l' hypertension moyenne solitaire. Press Med 39 (1931) 1789