Nicotinyl alcohol

  • Pyridylmethanol
  • Pyridin-3- ylmethanol (IUPAC)
  • C04AC02
  • C10AD05
  • Peripheral vasodilator
  • Lipid-lowering agents

Liquid

1.14 g · cm -3 ( 20 ° C)

-7 ° C

259 ° C

4.9 (25 ° C)

1.545 at 20 ° C.

Attention

1000 mg · kg -1 ( LD50, mouse, i.v.)

Template: Infobox chemical / molecular formula search available

Nicotinyl (also Pyridylmethanol ) is no longer in trade befindlicher drug which has been used for the treatment of dyslipidemia.

Clinical information

The drug is indicated for hyperlipoproteinemia type II - V Fredrickson. He also has a peripheral vasodilator effect ( vasodilation ).

Pharmacological properties

Nicotinyl alcohol reduces the total cholesterol, VLDL -, LDL-cholesterol and triglycerides in the blood serum, by decreasing the synthesis of VLDL. It is oxidized to nicotinic acid in the liver.

CAS registry number PubChem Anatomical Therapeutic Chemical Classification System DrugBank Dangerous Substances Directive (67/548/EEC) Active ingredient Donald S. Fredrickson Very Low Density Lipoprotein Serum (blood)
603381
de