Octreotide

  • CAS Number: 83150-76-9

Octreotide is a synthetic analog of the peptide hormone somatostatin, which is used as drug. Octreotide consists of eight amino acids ( D-Phe- cyclo [ Cys -Phe- D-Trp -Lys -Thr -Cys ] -Thr ( ol) ).

In Germany octreotide (, GEP-NETs, eg carcinoids ) approved for the treatment of acromegaly and certain gastrointestinal tumors.

About DOTA coupled to 111Indium or 68Gallium ( Edotreotid, DOTATOC ) it is in the somatostatin receptor scintigraphy, or in positron emission tomography (PET ) was used for detection ( diagnosis ) of these tumors. For therapeutic purposes ( radionuclide ), beta emitters, such as 90Yttrium or 177Lutetium be used

Octreotide can be used for the treatment of cluster headache attacks when other drugs are ineffective or contraindicated.

Trade names

Bendatreotid (D), Sandostatin (D, A, CH), octreotide (A), Siroctid (A ) and a generic (D)

CAS registry number Anatomical Therapeutic Chemical Classification System DrugBank Structural analog Active ingredient
613493
de