Phosphopantothenate—cysteine ligase

Phosphopantothenat -cysteine ​​ligase ( also Phosphopantothenat cysteine ​​synthase short PPC synthase gene: PPCS ) is the enzyme that catalyzes the attachment of Phosphopantothenat cysteine ​​. This is the second reaction step in the biosynthesis of coenzyme A, which occurs in most organisms.

Catalysed reaction equilibrium

ATP AMP PPi

(R )-4'- Phosphopantothenat is condensed on L- cysteine ​​under ATP consumption. The bacterial enzyme works more effectively with CTP.

Human Genome Organisation Condensation reaction
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