Robert Hegglin

Robert Marquard Hegglin ( born May 5, 1907 in Schönbrunn near train, † November 22, 1969 in Zurich ) was a Swiss internist and cardiologist.

Family

He was a doctor's son Carl Hegglin and his wife Mathilde Durrer. The grandfather was also a doctor. Among the ancestors also politicians and historians were.

Education and work

After completion of the district school train Hegglin studied at the Universities of Geneva, Munich, Berlin, Paris and Zurich medicine. This was followed by further training at the Pathological Institute in St. Gallen and at the University Hospital in Zurich, here were Otto Naegeli and Wilhelm Löffler his teachers.

While the Zurich assistant years he occupied himself mainly with cardiac problems. He received his doctorate in 1934. From 1938 to 1945 he worked as a senior physician at the Medical University Hospital and dealt with infectious diseases and hematology. 1943 Hegglin put his habilitation thesis ago, received in 1944 the venia legendi of Internal Medicine and held as a private lectures on differential diagnosis of internal diseases.

From 1947 he worked as a specialist in internal medicine and cardiology in Zurich. The position of the chief doctor of the Medical Clinic of the Cantonal Hospital St. Gallen, he took over in 1954, three years later, he received a professorship at the clinic in Zurich (1957).

Performance

Focus of clinical and scientific work were the areas Hegglins respiratory infections, electrocardiography, hematology and cardiology. His main work is the differential diagnosis of internal diseases, which ( with W. Siegenthaler Editor) became the standard work on the practical medical work, 16 editions experienced and appeared in numerous foreign language editions.

In addition, he was co-editor of the journal Cardiologia, a publication of the Swiss Society of Cardiology.

Hegglin eponyms

  • Hegglin syndrome syndrome of energetic- dynamic cardiac insufficiency as a metabolic disorder of the heart muscle that affects the process of muscle fiber contraction. The ECG can be found as an expression of repolarization disturbance, a prolonged QT interval with relative shortening of the mechanical systole. Clinically, the syndrome can be seen only with the simultaneous registration of ECG and heart sound, it is the second heart sound incidence by more than 0.02 seconds before the end of the T wave in the ECG.
  • Hegglin Holzmann formula as habilitation thesis Hegglin 1943 published a summary of work on the subject of prolonged QT interval on the electrocardiogram, in which he assessed the significance of the QT interval clinical aspects. Determining a pathological condition for the QT interval is the determination of the duration of physiological ventricular excitation.
  • Hegglin quotient The quotient value is used for the indicative quantitative calculation of a left- to-right shunt from the arterial indicator dilution curve.
  • Hegglin characters early onset, thereby seemingly vanishing, second heart sound ( " Woodpecker beat phenomenon " ), such as heart failure.
  • Hegglin Maier- heat resistance test diagnosis of paroxysmal nocturnal hemoglobinuria ( Marchiafava - Micheli type ), an acquired hemolytic anemia with good prognosis.
  • Fanconi -Hegglin syndrome by Guido Fanconi (1892-1979) in 1936 and 1941 described Hegglin pseudoluetische, subacute bronchopneumonia hilifugale viral etiology with Wassermann -positive pulmonary infiltrate.
  • May-Hegglin anomaly May of 1909 and 1945 Hegglin described. It is a polyphyletic development disorder, a family panmyelopathy with ripening disorders of polymorphonuclear leukocytes and thrombocytopathy a rare constitutional anomaly with autosomal dominant inheritance, which can be defined by " giant platelets " with thrombocytopenia from other thrombocytopenia. The prognosis is good.

Works

  • Chemotherapy of pneumonia. 1942
  • The prolonged QT interval on the electrocardiogram. Arch circulation researchers 13 (1943) 171
  • The polyphyletic maturation disorder. 1945
  • L' insuffisance énergétodynamique. Cardiologia 15 (1949 ) 65
  • Differential diagnosis of internal diseases (edited by W. Siegenthaler ). 1952
  • Circulatory diagnostics with the dye dilution method. Stuttgart 1962
Heart sounds Lung May–Hegglin anomaly Autosome Dominance (genetics) Integrated Authority File
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