Alfred Einhorn
Alfred Einhorn ( born February 27, 1856 in Hamburg, † March 21, 1917 in Munich) was a German chemist.
Life
Unicorn was the son of a Hamburg merchant. After the early death of his parents, he grew up with relatives in Leipzig and attended a secondary school in Berlin. After studying chemistry in Leipzig, he did his military service in Mannheim.
From winter semester 1878/79 he started his PhD with Lothar Meyer Institute of Organic Chemistry of the University of Tübingen. He received his doctoral thesis on " Isopropylphenylketone " 1882 Habilitation place with Adolf von Baeyer in Munich. His habilitation thesis on " β - lactones " not not enough apparently in Munich the claims, 1885 at the Technical University of Darmstadt, but in 1886 at the Polytechnic School of Aachen. Here he was awarded the title of Royal. Awarded the Prussian professor.
In 1891 he got a job at the LMU Munich and married shortly thereafter in Munich. He died after great suffering in the age of 61.
Work
His research focused on the synthesis without side effects and cocaine -like local anesthetics. As a useful synthesis methods have been known
Among the approximately 100 new substances may be found
- Ortho form of ( 4-amino- 3-hydroxybenzoic acid methyl ester ), 1887, effective, but water-insoluble
- Nirvanin, effective, water soluble, but locally irritant
- Novocain (4- aminobenzoic acid - β - diethylaminoethyl ester ), 1905, effective, water soluble and non-irritating locally compatible
Nirvanin
Novocaine procaine = (1905 )
Benzocaine (today)
Lidocaine (today)
Tetracaine (today)
Novocain was medically examined by the surgeon Heinrich Braun and Arthur Laewen and is the standard local anesthetic for many decades to become. It was at that time in front of the inking units. Meister Lucius & Brüning adopted AG and now bears the international non-proprietary name procaine
Famous people of A. Einhorn
In Unicorn doctorate et al Arthur Green Oak (1890 in Aachen ) and Richard Willstätter (1894 in Munich). Willstätter the first successful identification of nitrogenous breakdown products of cocaine, whose true identity was only 20 years later elucidated by Willstätter.