Ambazone

  • P- benzoquinone - guanylhydrazone thiosemicarbazone
  • [4 - (2 - ( Diaminomethyliden ) hydrazinyl ) phenyl] iminothioharnstoff (IUPAC)

R02AA01

Copper- brown crystals

Antiseptic

193 ° C.

750 mg · kg -1 ( LD50, rat, oral)

Template: Infobox chemical / molecular formula search available

Ambazon is a drug which has been used as an antiseptic in the mouth and throat. It was patented in 1957 by Bayer under the trade name Iversal ®, but is no longer commercially available.

Chemically, Ambazon a functional derivative of 1,4- benzoquinone (p- benzoquinone ). The compound has strong basic properties.

Synthesis

The synthesis is carried out starting from Ambazon of 1,4-benzoquinone in two steps by reaction with aminoguanidine, and thiosemicarbazide.

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