Aminopyridine

The aminopyridines form a group of substances of organic compounds belonging to the heterocyclic compounds in chemistry (more precisely, heteroaromatic) counts. They consist of a pyridine ring which is substituted with an amino group (-NH2). Due to the different arrangement of three structural isomers with molecular formula C5H6N2 result.

Properties

The aminopyridines are colorless to yellowish solids with a pyridinartigen odor. They are soluble in water and alcohols. 4- aminopyridine, which has the highest symmetry, has the highest melting point.

Use

4-aminopyridine is used for the preparation of 4- halopyridines and pharmaceuticals. It even serves as a bird poison and medicine as a reversible potassium channel blockers ( eg multiple sclerosis ).

4-aminopyridine in 2010 by the U.S. Food and Drug Administration under the U.S. Non-proprietary Names ( USAN ) dalfampridine admitted for supportive treatment of multiple sclerosis. An application for the European Union was rejected for the time being due to insufficient risk-benefit ratio. A decision by the Swiss authorities is still pending.

Related compounds

• Diaminopyridines C5H7N3
• Triaminopyridine C5H8N4
• Methylaminopyridine C6H8N2
• Dimethylaminopyridines C7H10N2