Center for Integrated Protein Science Munich

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The Center for Integrated Protein Science Munich ( CIPSM ) is a scientific cluster of excellence based in Munich. It is a consortium of research groups from the Ludwig- Maximilians- University of Munich, Munich University of Technology, the Helmholtz Zentrum München and the Max Planck Institutes for Biochemistry and Neurobiology in Martinsried. The center deals with isolated proteins to proteins in living organisms, using methods in biophysics, biochemistry, medicine and biology apply.

Objectives

Proteins play an important functional role and structure -forming, which is not yet fully understood in detail, as biological macromolecules for all living organisms. By study of isolated proteins to proteins in living organisms (for example, zebrafish, or Escherichia coli ), in particular with regard to interactions structural effects (for example, protein folding, structure of protein complexes, interactions of proteins with nucleic acids and manipulation of protein function ) and neurodegenerative diseases, is basic knowledge of these macromolecules can be obtained which could enable advances in biomedicine and biotechnology in the future.

Organization

The Cluster of Excellence is divided into six areas of research.

Each area (AF) is represented by two coordinators who decide after consultation with the Board on the appointment of new professors and from among the board of four researchers and a member which is in charge of Family and Women Promotion choose. The members of the Board are primarily responsible for research, teaching and promotion of young academics and represent the cluster in front of the lines of their respective universities. The Chairman of the Board and his deputy shall, in particular, the care and recruitment of junior professorships. The group leader ( divided into Principal Investigators and Associate Investigators ) meet once a year in the General Assembly and decide on the allocation of financial resources. The leadership of the working groups is individual and personal responsibility of the group leader. Regular communications between group leaders and coordinators of the research field allow an integrated management of the cluster. The role of the speaker cluster of excellence also extends to the representation of the interests of the cluster compared to the participating universities and institutions, which is why he leads negotiations on matters of teaching, funding and staff with them. The management and monitoring of all approved for the financial year funding, the setting of the staff, the management of the entire cluster matters, the purchase of major equipment and the organization of events such as symposia, conferences and workshops (see events and conferences ), as well as the processing applications and public relations fall within the remit of the manager.

Committee on Family and Women Promotion ( AFF )

The promotion of female researchers in CIPSM done by the AFF funding program with the objectives, the proportion of scientists with postdoctoral or professor and scientists to increase / inside with children, scientists in leadership positions. The Committee is chaired by the Executive Board member who is specifically responsible for Family and Gender Equality. This education program is intended to reduce the barriers of time caused by the parents on the academic career. Young scholars with child ( ren) may under the program a vacancy for a Technical Assistant (TV -L E9) are provided for the support of research, in addition, at the request of a domestic help are granted to domestic support. For young / inside with child ( ren) up to three years runs the CIPSM also a crèche. A mentoring program is designed to support a successful appeal of female scientists and symposia with senior scientists will allow researchers insight into career paths and experiences and encourage scientific exchange.

Financing

The funds from the CIPSM be provided as part of the Excellence Initiative of the Federal Republic of Germany and the Federal States in cooperation with the Deutsche Forschungsgemeinschaft available and allocated demand-driven.

Individual grants of scientists from the research cluster include project- related funding of doctoral and postdoctoral positions, subsidies for the purchase of major equipment and the promotion of symposia and special lectures in addition to promoting within the framework of women's and family support.

Research results and awards

Besides the selection of CIPSM cluster to a selected place in the land of ideas, several CIPSM - researchers were awarded for the research results achieved in the framework of its work on the Cluster of Excellence:

  • Thomas Carell received the Otto Bayer Award 2008, the Bayer Science & Education Foundation.
  • Patrick Cramer in 2007, the Philip Morris Research Prize for the detailed structural analysis of RNA polymerase II.
  • Magdalena Götz received the Gottfried Wilhelm Leibniz Prize 2007 of the German Research Foundation in recognition of her work in the field of the molecular basis of brain development.
  • Elena Conti got together with Dr. Elisa Izaurraldevom Max Planck Institute for Developmental Biology in Tübingen, the Gottfried Wilhelm Leibniz Prize 2008 of the German Research Foundation for " fundamental new insights into the intracellular RNA transport and RNA metabolism ."
  • Stephan Sieber and Thomas Hooper received the Innovation Award of the bioregions in Germany in 2008 for the study of beta- lactones for the treatment of diseases which are resistant to conventional antibiotics.
  • Horst Kessler received the 2008 Josef Rudinger Award of the European Peptide Society for his contributions to peptide chemistry.
  • Heinrich Leonhardt in 2008 with the binder Innovation Award for the development of fluorescent, antigen-binding single domain antibody, which can be expressed in living cells, excellent.
  • Thomas Cremer in 2009 received the Schleiden Medal of the German Academy of Natural Scientists Leopoldina for his formative work in the field of nuclear architecture.

In addition, the Federal Ministry of Education and Research of the CIPSM research groups Leonhardt and Schotta promotes cooperation "Experimental and theoretical methods for dissecting the dynamics of epigenetic gene silencing in living cells" with the University of Heidelberg.

Events and conferences

  • Graduate School Life Science Munich ( LSM): An international program for gifted graduate or master's graduates in the fields of anthropology, biochemistry, cell biology, ecology, evolution, genetics, microbiology, plant sciences, systematics and zoology with lectures, seminars and workshops.
  • CIPSM - Harvard Young Scientists' Forum ( YSF ): A study initiated by CIPSM annual event to stimulate interdisciplinary exchange between students and postdocs at Harvard University and the Ludwig- Maximilians- University of Munich.
  • CIPSM - ceremony at the Deutsches Museum on May 4, 2009 as part of the " Land of Ideas" festival with presentations on current results of protein research of the cluster.
  • Elmau Conference 2008 and monastery Irsee Conference 2009: conferences on themes related to protein research in collaboration with Bayer Schering Pharma AG.
  • CIPSM Lecture by Prof. Martina Havenith as part of the promotion of women ( 2009).
  • Alps Forum 2009: CIPSM since 2008 supports the Alps Forum of the German Chemical Society - Young Chemists Forum Munich, which is held annually in Oberammergau to undergraduate and postgraduate students of chemistry and related sciences with the opportunity to inform themselves about possible career paths and career goals of chemists to meet company representatives and interesting employer know.
  • WOMAN 2.0 " wife & mother & scientist how is that even possible? " (2009): Information Event for Students of the natural sciences, particularly chemistry, biology and pharmacy, about career possibilities and perspectives of female scientists at the Ludwig- Maximilians- University of Munich as part of the promotion of women.
  • CIPSM - young - Mini Symposium: lecture and discussion event at the Technical University of Munich on trends and new developments in protein research.
  • Synthesefest: lecture at the Ludwig- Maximilians- University of Munich on Organic Chemistry with international speakers from research and industry.

In addition, the CIPSM clusters organized

  • Chromatin assembly and Inheritance of Functional States, 2nd Transregio 5 Symposium ( 2007),
  • The European Cooperation in the Field of Scientific and Technical Research " COST Meeting" (2008),
  • The EMBO Workshop " Gene Transduction in Yeast " (2008),
  • The 16th Conference Lecture ORCHEM 2008, in cooperation with the German Chemical Society and the Liebig association of Chemistry
  • The 4th International Conference on the Hsp90 Chaperone Machine ( 2008).

Science Comment

The Science Project was established in 2009 by Comment CIPSM to create an opportunity to comment on publications of relevant journals in the disciplines of chemistry, biology, pharmacy and medicine objectively and discuss with the ultimate aim to facilitate international communication of research results. The registered user, it is possible to express terms of taking a publication comments and criticisms to the public or the publication to discuss publicly. Science Comment serves as a database to provide users with an assessment of the quality of a spread in a publication outcome before its application. The so- potential testing a published result on feasibility saves users time and money.

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