Corwin Hansch

Corwin Hansch ( born October 6, 1918 in Kenmare (North Dakota); † May 8, 2011 in Claremont ( California)) was an American chemist (organic chemistry). He was a professor at Pomona College and is considered one of the founders of quantitative structure - activity relationship (QSAR ).

Hansch studied at the University of Illinois, Chicago, with a bachelor 's degree in 1940 and received his doctorate in 1944 at New York University. He then worked in the Manhattan Project at the University of Chicago and at DuPont, where he was also briefly a research chemist. In 1946 he went to Pomona College, where he was Profeesor.

He was a visiting scientist at the ETH Zurich and the Ludwig- Maximilians- University of Munich. He had an honorary professorship at the University of Beijing.

It shall work in the early 1960s as the founder of QSAR, the correlation of biological activity with chemical structure ( often simply Hansch equations or Hansch analysis called ), with many applications in computer-aided drug design. He wrote more than 300 publications.

He was Guggenheim Fellow, received the 1975 Tolman Award and Member of the Royal Society of Chemistry. He was inducted into the Hall of Fame for Chemical Physics of the American Chemical Society.

Writings

• C. Hansch, PP Maloney, T. Fujita and RM Muir, Correlation of Biological Activity of Phenoxyacetic Acids with Hammett substituent Constants and Partition Coefficients, Nature 1962, 194, 178-180
• C. Hansch, RM Muir, T. Fujita, PP Maloney, CF Geiger and M.Streich, The Correlation of Biological Activity of Plant Growth Regulators and Chloromycetin Derivatives - with Hammett Constants and Partition Coefficients, J. Amer. Chem Soc. 1963, 85, 2817-2824.