David Paul von Hansemann

David Paul Hansemannplatz, 1901 by Hansemannplatz ( born September 5, 1858 in Eupen, then the Kingdom of Prussia, now Belgium, † August 28, 1920 in Berlin) was a German pathologist. He formulated one of the first theories about the origin of cancer.

Career and work

He came from a very wealthy family and was the son of Gustav Hansemannplatz (1829-1902), who was raised as a reindeer in Charlottenburg with his descendants on 18 January 1901 in Berlin in the Prussian nobility, and the forelands Mathilde ( 1827-1880 ). His grandfather was a merchant and banker David Hanse man, his uncle Adolph von Hanse man was one of the wealthiest men of the German Empire and his cousin was the chemist Daniel forelands.

1881 made ​​Hansemannplatz at Berlin's Friedrich- Wilhelm-Gymnasium graduated from high school. In the same year he began the study of medicine in Berlin. After three semesters, he went for one semester to Kiel and for three to Leipzig. His professors were there. Among others, Wilhelm His, Carl Ludwig, Ernst L. Wagner and Julius Friedrich Cohnheim 1886 Hansemannplatz was awarded his doctorate for Dr. med. After completion of the study and completing his military service, he became assistant pathologist Rudolf Virchow in Berlin. During his tenure there, he reported in 1890 by striking changes in cell nuclei and altered patterns of division, which he observed in slice preparations of 13 different cancers. Hansemannplatz saw between these changes and the development of malignant tumors is a connection. He postulated that the aberrant cell division for the increased or reduced content of chromatin are responsible in the cancer cells. His observations mark the beginning of tumor cytogenetics.

25 years later Theodor Boveri developed from the observations Hanse 's own work and the chromosome hypothesis of tumorigenesis, changes in the chromosomes of a cell ( aneuploidy) are a prerequisite for the transition from normal to malignant cell growth proliferation. Aneuploidy is observed in many cancers. Whether aneuploidy this however is the cause or just a consequence of cancer is controversial. See Peter Duesberg # aneuploidy -cancer hypothesis.

1907 examined Hansemannplatz the brains of Theodor Mommsen, Robert Bunsen and Adolf von Menzel ( "elite brain research").

Hansemannplatz was privy medical officer ( appointed in 1912 ) and prosector at Berlin's Rudolf Virchow Hospital. In 1912 he became a full professor of pathology. During World War II he was on the Eastern Front and was awarded the Iron Cross First Class. He was with Elisabeth, born Walter (1863-1935), married and died of throat cancer in 1920 in Berlin.

Writings

• Atlas of malignant tumors. Publisher Hirschwald August, 1910
• The microscopic diagnosis of malignant tumors Publisher Hirschwald August, 1902
• Superstition in medicine and its danger to health and life. Publisher Teubner, 1914